Testicular Germ Cell Tumor

A germ cell tumor that originates from the TESTIS and inlcudes TERATOMAS; SEMINOMAS; EMBRYONAL CARCINOMAS; and YOLK SAC TUMORS. Genetic contribution is likely from multiple independent mutations in different genes that each confer moderate risk. Germline and somatic mutations in the BCL10 gene, and somatic mutations in KIT, BRAF, HRAS, KRAS, and STK11 have been identified. OMIM: 273300

Neoplasms: 1324753
- Neoplasms by Site: 4
  - Urogenital Neoplasms: 471
    - Male Genital Neoplasms
      - Testicular Neoplasms: 6597
        Testicular Germ Cell Tumor: 254
  - Endocrine Gland Neoplasms: 130
    - Testicular Neoplasms: 6597
      - Testicular Germ Cell Tumor: 254
- Neoplasms by Histologic Type: 2
  - Germ Cell and Embryonal Neoplasms: 4454
    - Testicular Germ Cell Tumor: 254
Urogenital Diseases: 126
- Urogenital Neoplasms: 471
  - Male Genital Neoplasms
    - Testicular Neoplasms: 6597
      - Testicular Germ Cell Tumor: 254
- Genital Diseases: 114
  - Male Genital Diseases: 2
    - Male Genital Neoplasms
      - Testicular Neoplasms: 6597
        Testicular Germ Cell Tumor: 254
- Male Urogenital Diseases
  - Urogenital Neoplasms: 471
    - Male Genital Neoplasms
      - Testicular Neoplasms: 6597
        Testicular Germ Cell Tumor: 254
  - Male Genital Diseases: 2
    - Male Genital Neoplasms
      - Testicular Neoplasms: 6597
        Testicular Germ Cell Tumor: 254
Endocrine System Diseases: 968
- Endocrine Gland Neoplasms: 130
  - Testicular Neoplasms: 6597
    - Testicular Germ Cell Tumor: 254
- Gonadal Disorders: 30
  - Testicular Diseases: 49
    - Testicular Neoplasms: 6597
      - Testicular Germ Cell Tumor: 254

Lenka Wachsmannová Selected Research

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Disease

Drug/Important Bio-Agent (IBA)